Management of critical COVID-19 Advanced non-invasive respiratory support: high-flow nasal oxygen and non-invasive ventilation- Part 2 – World Health Organization


For patients on HFNO with persistent hypoxaemia or respiratory distress:

• Check the equipment: inspect the exterior of the machine, the tubing (circuit), the prong for
any sign of mechanical damage, confirm it fits and the filters are in place. Ensure the settings
are appropriate and flow is maximized.

• Check the oxygen source: there is sufficient oxygen available and flowing through the
device. If FiO2 > 50% of oxygen is needed, the device must have a blender.

• Check there is no obstruction with secretions: patients with COVID-19 may have very thick
secretions which may block small and large airways and cause sudden respiratory